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Flavonas e avonóis: novas descobertas sobre sua estrutura química e fun o biológica. =
Magna Maria Macedo Ferreira,Adriano Henrique Cruz de Oliveira,Nádia Souza dos Santos
Agro@mbiente On-line , 2008,
Abstract: Nos últimos anos, diversos pesquisadores no mundo têm estudado a diversidade química das flavonas e dos flavonóis, os quais s o tipos de flavonóides que, por sua vez, fazem parte de um grupo particular de metabólitos secundários, os compostos fenólicos. Os metabólitos secundários s o compostos organicos produzidos pelos vegetais, aparentemente sem fun o direta no seu crescimento e desenvolvimento, os quais incluem terpenos, composto fenólicos e compostos nitrogenados. Esses compostos s o restritos a uma espécie vegetal ou a um grupo de espécies relacionadas. Os fl avonóidesconstituem a maior classe de fenólicos vegetais. As fl avonas e os fl avonóis s o protetores químicos que absorvem luz em comprimentos de onda mais curtos do que àqueles visíveis ao olho humano, protegendo as células vegetais dos danos causados pela fotoxida o. Além dessa fun o protetora, ainda funcionam como sinais atrativos para insetos como as abelhas, que enxergam na faixa extrema do ultravioleta. Os flavonóis em uma flor formam padr es simétricos de listras, pontos ou círculos concêntricos chamados de guias de nectário. Tendo-se um melhor conhecimento da estrutura químicadesses fl avonóides, é possível se entender mais sobre a dinamica biológica da rela o polinizador-nectário, o que poderápermitir que, num futuro próximo, se manipule essa rela o para fins n o apenas de aumento na produtividade de algumas plantas cultivadas, mas também para fins de conserva o do meio ambiente, uma vez que o uso abusivo de defensivos químicos na agricultura tem diminuído a popula o de polinizadores em muitos agroecossistemas. = In last years, various researchers in world has studied the flavones and flavonols chemical diversity, which are types of flavonoids which makes part of a particular group of secondary metabolites, the phenolic compounds. The secondary metabolites are organic compounds produced by vegetables, apparently without direct function in your growth and development, which included terpenes, phenolic compounds and nitrogen compounds. Theses compounds are restrict to a vegetable specie or to a group of connected species. The fl avonoids are the larger class of vegetable phenolics. The fl avones and flavonols arechemical protectors which absorb light in wave length more shorts than the visible to human eye, protecting the vegetable cells against the damage caused by photoxidation. Moreover, the flavones and fl avonols have function of attractive signals to insects as the bees, which look in extreme band of the ultra-violet. The fl ower flavonol form symmetric standard of stripes
Ocorrência de moscas-das-frutas (Diptera: Tephritidae) em mangueiras (Mangifera indica L.) em Boa Vista, Roraima = The occurrence of fruit fly (Diptera: Tephritidae) in mango (Mangifera indica L.) in Boa Vista, Roraima
Adriana Bezerra Lima,Antonio Cesar Silva Lima,Adriano Henrique Cruz Oliveira,Nádia Souza dos Santos
Agro@mbiente On-line , 2012,
Abstract: Um estudo foi conduzido no período de junho de 2007 a janeiro de 2008, em pomares comerciais de manga das variedades: Tommy Atkins, Haden e Palmer sendo 3 ha de cada cultivar, localizado na regi o do Bom Intento no Município de Boa Vista. Os espécimes de moscas-das-frutas foram coletados, por meio de armadilhas, confeccionadas com garrafas pet, que foram penduradas na copa das árvores a 1,60 m de altura. Como atrativo alimentar foi utilizado 200 mL de suco de maracujá a 30%. Foram utilizadas nove armadilhas, sendo uma armadilha por hectare. Semanalmente as armadilhas eram examinadas, ocasi o em que se substituía o atrativo e os insetos capturados retirados e colocados em frascos de vidro devidamente etiquetados e transportados ao Laboratório de Entomologia do Centro de Ciências Agrárias da Universidade Federal de Roraima. As identifica es dos espécimes foram feitas no Instituto Nacional de Pesquisa da Amaz nia - INPA. No período de oito meses foram coletados 24 espécimes adultos do gênero Anastrepha (nove fêmeas e 15 machos). Quatro espécies foram identificadas: A. serpentina, A. striata, A. obliqua e A. turpinae. A maior frequência foi A. serpentina (44,44%), seguida de A. striata e A. obliqua ambas com 22,22% e A. turpinae com 11,11%. Os meses de maior ocorrência de Anastrepha spp. foram junho, julho e agosto. Este é o primeiro registro da espécie Anastrepha turpinae Stone, 1942, em Roraima. The study was done during th period of June 2007 to January of 2008, in commercial mango orchards having: 3 ha of cv. Tommy Atkins, 3 ha of cv. Haden. and 3 ha of cv. Palmer, located at Bom Intento in the municipal district of Boa Vista - RR. The specimens of fruit flies were collected, by trapping, made with transparent bottles pet, which were hung in the cup of the trees at 1.60 m of height. 200 mL of passion fruit juice (30%) was used as an attractant feed; 9 traps were used, being one trap for hectare. Weekly The traps were examined weekly, during which the bait was substituted and the capture insects removed, placed in labeled glass flasks properly and transported to the Laboratory of Entomology, Centro de Ciências Agrárias, Universidade Federal de Roraima - UFRR. The identification of the specimens was done at the Instituto Nacional de Pesquisa da Amaz nia - INPA. a - INPA. During the period of eight months 24 adult specimens of Anastrepha were collected (9 females and 15 males). Four species were identified: A. serpentina, A. striata, A. obliqua and A. turpinae. The highest frequency of trapped insects was A. serpentina (44.44%), followed by A. striata and
Multidisciplinary experience in the selection of patients for tubal sterilization
Barini, Ricardo;Pinto-Neto, Aar?o Mendes;Costa, Lúcia Helena Sim?es;Barros, Arlete de Souza;Marchi, Nádia Maria;Ferreira, Lúcia de Lourdes;Bueno, Ermelinda Maria;Murayama, Akemi;Nascimento, Cláudia Sampaio do;Hinz, Laise Potério dos Santos;Almeida, Olivia Josane Barreto de;
Sao Paulo Medical Journal , 1995, DOI: 10.1590/S1516-31801995000100009
Abstract: results of the use of a special protocol for evaluation of patients requiring tubal ligation is presented after applied by a multidisciplinary group. the authors conclude that the use of defined parameters of age, parity, marital union duration, number of children alive and the presence of maternal clinical pathology are useful to identify patients with smaller chances of regret after surgery.
Prevalence and Incidence of Hand Osteoarthritis and Upper Limb Complaints in Patients with Knee Osteoarthritis. Correlations among Functionality, Grip Strength, Changes in Body Mass Index and Symptoms among Patients in an Educational Osteoarthritis Program  [PDF]
Vinicius Canello Kuhn, Daniele dos Santos Scarcella, Rosana Mayumi Suzuki, Ligia Cortez de Almeida, Nádia Lucila Rocha Brito, Marcia Uchoa de Rezende
Open Journal of Orthopedics (OJO) , 2016, DOI: 10.4236/ojo.2016.61001
Abstract: Objective: To evaluate the prevalence of hand osteoarthritis (hOA) in a population with knee osteoarthritis (KOA) at baseline and one year following the administration of a multi-professional OA educational program correlating symptoms and changes in BMI with function questionnaires of the upper limbs and direct grip strength measurements. Design: Epidemiological study of the prevalence of hand OA in patients with knee osteoarthritis. The Stanford Health Assessment Questionnaire instruments (HAQ); Disabilities of the Arm, Shoulder and Hand* (DASH); grip strength; and finger pinch were utilized, and the upper limbs symptoms were verified at baseline and one year following the educational program. Results: The prevalence of hOA was 23.7% at baseline and 47.4% at one year (incidence of 31.8% per year). The HAQ indicated that patients who did not alter or increased their BMI experienced worsened global strength, whereas patients who reduced BMI improved global strength (p = 0.041). Patients with higher initial BMIs experienced less improvement in the HAQ (r = -0.148, p = 0.041). The DASH results improved, but the right and left tripod grip worsened in all patients, irrespective of BMI change (p < 0.05) or symptoms at baseline and reassessment (p < 0.05). Pinch strength (right and left tripod and left pulp-pulp) was higher in patients without symptoms at baseline (p = 0.048, p = 0.045 and 0.033, respectively). Conclusions: The prevalence of hand OA increased for patients with OA undergoing an educational program irrespective of improved upper function and regardless of BMI change. Patients who decreased their BMI improved their global strength.
Cilindros capilares: relato de três casos e revis?o da literatura
Minelli, Lorivaldo;Gon, Airton dos Santos;Sales, Nádia Cristina Miguel de Marque;
Anais Brasileiros de Dermatologia , 2006, DOI: 10.1590/S0365-05962006000200007
Abstract: hair casts are small white yellowish keratinous structures that totally wrap the hair shaft. they are characterized by asymptomatic, semifirm, tannish, freely movable, cylindrical masses, distributed along the scalp hair. this condition has been found in three women, whose case histories are described.
Esclerose múltipla: estudo de pacientes com a forma surto-remiss?o cadastrados na Secretaria de Estado da Saúde de Minas Gerais
Santos, Eustáquio Claret dos;Yokota, Mitico;Dias, Nádia Fernanda Rezende;
Arquivos de Neuro-Psiquiatria , 2007, DOI: 10.1590/S0004-282X2007000500032
Abstract: multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system. the recommended treatment for the relapsing-remitting form is carried out with the immunomodulatory drugs, which are provided, in belo horizonte, by minas gerais secretary of state for health (mg/ssh). we analyzed data of 283 patients registered at exceptional drug program (immunomodulators) of ses/mg from may to october 2004. there was predominance of females (3.7:1) and the mean age was 38.4±10.7 years old. the first clinical manifestations were 29.7±10.2 years old. the initial symptoms included sensorial (46.4%), visual (33.1%), brainstem/cerebellar syndromes (30.1%) and motor (pyramidal) syndrome (25.9%). the symptoms observed in subsequent relapses were motor (22.3%), brainstem/cerebellar syndromes (18.9%), visual (18.9%) and sensorial findings (9.6%). in 234 brain mri and 109 spine mri there were demyelinating lesions at 97.4% and 85.3% respectively. we compared our findings with other series described on brazilian literature.
Indexes of spatio-temporal change to reconstruct the historical evolution of a coastal region: case study: S?o Sebasti?o Island - SP
Bertolo,dia S.;Lima, Guilherme T. N. P. de;Santos, Rozely F. dos;
Brazilian Journal of Oceanography , 2010, DOI: 10.1590/S1679-87592010000700006
Abstract: the coastal regions of brazil have lost most of their distinct characteristics due to an intense, diverse, and long history of land use. the current scenario is the result of successive changes which have taken place since the colonization of brazil. these changes should be taken into account in environmental planning since the decisions about the future depend on the understanding of past changes. in this regard, the aim of this study was to identify and quantify the spatio-temporal changes in land use in a coastal region, using principles of landscape ecology and scenario construction. the case study was the s?o sebasti?o island, divided into 61 watersheds, off the northern coast of s?o paulo state (brazil). the study involved the development and application of a methodology to interpret the historical dynamics of the island. the driving forces were identified and indexes of change were calculated to define the phases of occupation of the island. five phases of occupation of the coastal landscape were mapped: preservation, conservation, regeneration, exploitation and urbanization. these phases represent a pattern of internal heterogeneity, sometimes positive (environmental conservation), and sometimes negative (environmental degradation).
Flavonoid action in second intention healing in surgically-induced clean wounds in Wistar rats A o dos flavonóides na cicatriza o por segunda inten o em feridas limpas induzidas cirurgicamente em ratos Wistar
Alno Poiares Vieira,Nádia Rosa dos Santos,José Henrique Saraiva Borges,Mariana Pinheiro Alves Vincenzi
Semina : Ciências Biológicas e da Saúde , 2008,
Abstract: Flavonoids represent one of the main groups of substances with pharmacological activities in plants. They are used to increase the effectiveness of the healing process in wounds and ulcers. Propolis and green tea (Camellia sinensis) are two products rich in flavonoids that present indications as: anti-inflammatory antibacterial, antioxidant and healing ones. The present study aims to evaluate the action of propolis and green tea on the healing process in clean wounds. The wounds were produced in 20 Wistar rats. In each rat two symmetrical lesions of 11 mm diameter were induced using a surgical punch. The lesions were located on the left and right sides of the lateral thoracic region. Later the rats were divided in 2 groups. Group 1 – treated with 0.9% physiologic solution (left side), and with green teabased cream (Camellia sinensis) at 20% (right side); Group 2 – treated with base cream (left side) and treated with propolis-based cream at 20% (right side). The lesions diameters were measured every three days. The lesions healing was observed after 15 days, and there was no significant difference among the treatments, despite groups treated with green tea and propolis cream presenting better evolution during the treatment. Os flavonóides representam um dos principais grupos de substancias com atividades farmacológicas em plantas, e s o utilizados para elevar a eficácia do processo de cicatriza o em feridas e úlceras. A própolis e o chá verde (Camellia sinensis) s o dois produtos ricos em flavonóides que apresentam indica es como antiinflamatórios, antibacterianos, antioxidantes e cicatrizantes. O presente estudo tem por objetivo avaliar a a o da própolis e do chá verde no processo de cicatriza o em feridas limpas. As feridas foram produzidas em 20 ratos Wistar, e em cada rato, foram induzidas duas les es simétricas de 11 mm de diametro, utilizando-se um Punch cirúrgico. As les es se localizavam do lado esquerdo e direito da regi o torácica lateral. Posteriormente, os ratos foram divididos em 2 grupos. Grupo 1 – grupo tratado com soro fisiológico à 0,9% (lateral esquerda) e com creme a base de chá verde (Camellia sinensis) à 20% (lateral direita); Grupo 2 - grupo tratado com creme base (lateral esquerda) e tratados com creme a base de própolis à 20% (lateral direita). Os diametros das les es foram medidos a cada três dias. A cicatriza o das les es ocorreu em 15 dias, sendo que n o houve diferen a significativa entre os tratamentos, apesar dos grupos tratados com creme de chá verde e de própolis apresentaram melhor evolu o durante o tratamento.
Bond strength between acrylic resin and maxillofacial silicone
Marcela Filié Haddad,Marcelo Coelho Goiato,Daniela Micheline dos Santos,Nádia de Marchi Crepaldi
Journal of Applied Oral Science , 2012,
Abstract: The development of implant dentistry improved the possibilities of rehabilitation with maxillofacial prosthesis. However, clinically it is difficult to bond the silicone to the attachment system. OBJECTIVES: This study aimed to evaluate the effect of an adhesive system on the bond strength between acrylic resin and facial silicone. MATERIAL AND METHODS: A total of 120 samples were fabricated with auto-polymerized acrylic resin and MDX 4-4210 facial silicone. Both materials were bonded through mechanical retentions and/or application of primers (DC 1205 primer and Sofreliner primer S) and adhesive (Silastic Medical Adhesive Type A) or not (control group). Samples were divided into 12 groups according to the method used to attach the silicone to the acrylic resin. All samples were subjected to a T-peel test in a universal testing machine. Failures were classified as adhesive, cohesive or mixed. The data were evaluated by the analysis of variance (ANOVA) and the Tukey's HSD test (α=.05). RESULTS: The highest bond strength values (5.95 N/mm; 3.07 N/mm; 4.75 N/mm) were recorded for the samples that received a Sofreliner primer application. These values were significantly higher when the samples had no scratches and did not receive the application of Silastic Medical Adhesive Type A. CONCLUSIONS: The most common type of failure was adhesive. The use of Sofreliner primer increased the bond strength between the auto-polymerized acrylic resin and the Silastic MDX 4-4210 facial silicone.
Produ??o volumétrica de metano: dejetos de suínos
Souza, Cecília de Fátima;Campos, Josiane Aparecida;Santos, Claúdia Ribeiro dos;Bressan, Waleska Soares;Mogami, Cristina Akemi;
Ciência e Agrotecnologia , 2008, DOI: 10.1590/S1413-70542008000100032
Abstract: the present work was carried out to evaluate the swine wastes biogas potential yield, specifically the methane yield. the total solid content in the substratum was 6% composed by the solid waste diluted to water. the wastes was collected by scratching, in swine ending facilities, composed by boxes, in which the walls were constructed of masonry and the floor was constructed of cement. the experimental swines received corn and soybean balanced ration. the waste treatment system, in laboratorial scale, was composed by three batteries with eight digesters each, installed inside of 500 liters asbestos boxes, containing 270 liters of heated water. in each box, an eletric resistance and water pump were installed to mantain the temperature and to mix the heated water. the system was submitted to hydraulic retention times (hrt) of 30, 25, 15 and 10 days and to temperatures (t) of 25, 35 and 40 oc, with and whithout substratum agitation. it was evaluated, under these conditions, the organic matter degradation process and resultant methane volumetric yield (mp). the largest values of mp were observed in hrt of 10 days, at the temperature of 40 oc, in the digesters with substratum agitation.
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